PED Virus Treatment

Porcine Epidemic Diarrhea (PED) – Scour

Porcine Epidemic Diarrhea is caused by a coronavirus, a virus somewhat similar to that of which causes TGE. This virus is widespread in Europe particularly. The virus damages the villi in the gut thus reducing the absorptive surface, with loss of fluid and dehydration. After the introduction into a susceptible breeding herd, the disease is followed by a strong immunity over two to three weeks. The colostral immunity then protects the piglets. The virus disappears spontaneously from small breeding herds but tends to be maintained in finishing farms due to the repeated introduction and subsequent infection of susceptible pigs.

Acute Disease: This occurs where the virus is introduced into a susceptible population for the first time. In such cases up to 100% of sows may be affected, showing a mild to very watery diarrhea. Two clinical pictures are recognized: PED Type I only affects growing pigs where as PED Type II affects all ages including sucking pigs and mature sows. The incubation period is approximately 2 days and the disease episode lasts for 7 to 14 days. In sucking pigs, the disease can be mild or severe with mortalities up to 40%.

Diagnosis: This can be suspected on the clinical signs but it cannot be differentiated from TGE. If acute diarrhea is occurring in weaned and older animals on a growing/finishing farm with no symptoms in sucking piglets then this would suggest PED Type I. PED Type II would affect piglets. Virus particles from diarrhea samples can be identified under the electron microscope, but this would not differentiate PED from TGE. Blood tests must be conducted to look for rising antibody titres. An ELISA test is recommended for examining diarrhea samples or intestinal contents.

Symptoms

Sows:

  • This can vary from very mild “cow pat” feces through to watery diarrhea.
  • Loose feces.

Piglets:

  • Diarrhea.
  • Dehydration.
  • Mortality may be high.

Weaners & Growers:

  • Acute watery diarrhea with no blood or mucus.
  • Mortality is usually low but morbidity can be high.
  • When the virus is first introduced on to the farm there is a rapid spread of diarrhea across all breeding and growing pigs with almost 100% morbidity (pigs affected) within 5 to 10 days. The incubation period is 2 to 4 days.
  • Vomiting.

Present Treatment: Because this is a virus infection, there is no specific treatment, but often, secondary bacteria complicate the picture and presently broad-spectrum antibiotics such as neomycin can treat these framycetin, apramycin or trimethoprim/sulpha with only limited to no success.

Immunity: Optional treatment can be given to healthy adult pigs to develop their immunity. This treatment should be given and monitored by certified professional personal or by a veterinarian. Daily feces sample must be tested for spread of virus and monitored animal health daily on regular basis.
Optional Treatment: Not recommended otherwise monitored by professionals.
(If the virus enters the herd for the first time, it is important to ensure that all the adult animals become infected at an early stage to allow an early immunity to develop. This can be achieved by exposing sows to the diarrhea three times, two days apart via the drinking water. Mix scours or contaminated material into a bucket of water and use this as the source.)

TWO STEPS NATURAL MICROBIAL TREATMENT (SEBS 2-72) FOR PORCINE EPIDEMIC DIARRHEA (PED) VIRUS

STEP # 1- Specially designed Activator-PT given orally travels down to the intestines (gut) and seeks out the PED virus protein cell and attaches itself to the virus body and stays there until step #2 secondary treatment arrives. Activator is completely harmless and safe to the pig’s internal functions and will not affect any vital organs or blood chemistry.

STEP # 2 – SEBS 2-72 Microbes are specially designed to treat PED virus in conjunctions with Activator- PT step #1. These SEBS 2-72 Microbes are specifically trained to seek out Activators that attaches to the PED virus cell body in the gut. Activator-PT acts as a direct guide for SEBS 2-72 microbes and guide them to the correct cell body where activator is present and which is attached to the PED virus.

Activator-PT is a protein based food source for the SEBS 2-72 microbes, which only designed to attract SEBS 2-72 microbes. It will not interfere with healthy microbes or enzymes in the gut. PED virus becomes a food source for the SEBS 2-72 microbes which consumes, digests and destroys PED virus; then it will simply exit the body and will destroy itself.

Before Treatment with SEBS 2-72
Laboratory test must be conducted to diagnose PED virus presences before giving SEBS 2-72 microbial treatment. Clinical diagnosis and examination of feces samples must be performed with ELISA test or electron microscopy to confirm the proper diagnosis. PED must be differentiated from TGE by laboratory tests.

Treatment & Dosage:

For Sucking Baby Pigs: Step # 1-Activator give 50ml orally. Wait 2 hours before giving Step #2.

Step #2- SEBS 2-72 Microbes give 50 ml orally

Note: This treatment should be given at empty stomach and before feeding            every 24 hours. Normal feeding and water is recommended during this treatment. Give three treatments in 72 hour period. Collect fecal matter and send it to lab for virus testing. If lab results show positive, give two more additional treatments in 48 hours and follow above guideline. Treatment should be given and monitored in a controlled environment.

For Growing Pigs and Mature Sows: Step # 1-Activator give 100ml orally. Wait 2 hours before giving step #2.

Step #2- SEBS 2-72 Microbes give 100ml orally

Note: This treatment should be given at empty stomach and before feeding. Recommend to give one treatment every 24 hours. Normal feeding and water is recommended during this treatment. Give three treatments in 72-hour period. Collect fecal matter and send it to lab for virus evaluation. If lab results show positive, give two more additional treatments in 48 hours and follow above guideline and follow up with lab test

Results: At the end of three to five treatments cycle PED virus severity should decline and animals should begin to regain normal feeding cycle and regain energy and normalcy. If animal is still weak and having diarrhea and loosing water, give one additional treatment of step #1 and 2 every 24 hours until normal stool starts to form. Continue to feed and water animal during this treatment cycle.

Storage: SEBS 2-72 and Activator must be stored at temperature between 40°F to 50°F in cool dry place.

Shelf life: Shelf life is 3 to 4 months if stored properly as directed.

Warning: Do not mix this product with any other antibiotics, prescriptions or any type of vaccines.

Side Effects: Not Known. There are no side effects during and after the treatment. Overdose may cause constipations in younger pigs. Give plenty of clear liquid or water during this treatment.